The Cubs are set to start their first series in three weeks against the Cardinals.
In the past, Cubs pitchers have struggled to win games when they face the Cardinals, a team with a lot of potential to win the NL Central.
Quintana, however, is expected to start and give the Cubs an edge in Game 1.
In five career games against the Cards, Quintana has pitched to a 1.71 ERA with a 0.84 WHIP.
This season, he has thrown 27 1/3 innings with a 1,067 ERA with 13 strikeouts.
Quintanas career 3.31 ERA is second in the National League behind only Clayton Kershaw.
He also owns a 3.17 ERA with 19 strikeouts in nine postseason appearances.
In his career, Quintanas ERA is a career low 1.74.
The Cubs currently have a 1-2 record in the series and are currently one game behind the Cardinals in the NL Wild Card standings.
The Cardinals lead the NL in total bases (1,134) and home runs (137).